Post-COVID-19 syndrome (post-COVID, long-COVID) is new phenomenon in therapeutic practice which has been understudied so far. The majority of patients having recovered from the disease regardless of its form experience virus persistence up to 6-9 months after sickness. This is justified by presence of immunoglobulin M against SARS-CoV-2. Given that the basis of post-COVID-19 pathogenesis is microcirculatory disorders followed by tissue hypoxia development, cryotherapy acts upon microcirculatory bloodstream boosting microcirculation, improving hemorheology, regulating production of adrenal and pituitary hormones thus repairing all disordered functions. We have applied general and local therapy as a standard procedure at first and second stages of rehabilitation since May 2020 to more than 300 patients who have had various forms of COVID-19. This is combined with intravenous laser blood irradiation (365 nm and 635 nm wave length), carboxytherapy, magnet therapy, kinesiotherapy, osteopathy, medicine electrophoresis. After the first procedure patients have admitted the decrease of fatigue, blood pressure stabilization, absence of pain in the joints, no depression and anxiety but better sleep, more positive emotions, joy and hope. Procedures contribute to rise of oxygen saturation and absence of dyspnea. Hair loss stops and its recovery starts. Parameters of clinical blood analysis, blood-sedimentation test, CRP, ferritin, procalcitonin, coagulation parameter, blood sugar are stabilizing quickly. Overall, cryotherapy may be applied as an effective standard procedure for treatment of patients suffering from post-COVID-19 syndrome as well as combined with other treatment and rehabilitation procedures. That said, cryotherapy always has potentiating action.

Lyubov Palchikova 教授丨第二十一届世界冷冻大会发言：题目《冷冻疗法在综合治疗COVID-19后综合症中的病理依据》

后COVID-19综合征（post-COVID，long-COVID）是治疗实践中的一个新现象，至今尚未得到充分研究。大多数从疾病中康复的病人，无论其形式如何，都会在病后6-9个月内出现病毒持续存在。这是因为存在针对SARS-CoV-2的免疫球蛋白M而得到证实。鉴于COVID-19后发病机制的基础是微循环障碍，随后是组织缺氧的发展，冷冻疗法作用于微循环血流，促进微循环，改善血液流变学，调节肾上腺和垂体激素的分泌，从而修复所有紊乱的功能。自2020年5月以来，我们在康复的第一和第二阶段将一般和局部治疗作为标准程序应用于300多名患有各种形式COVID-19的患者。这与静脉注射激光血液照射（365纳米和635纳米波长）、磁疗、运动疗法、骨疗法、医学电泳相结合。第一次手术后，病人承认疲劳减少，血压稳定，关节没有疼痛，没有抑郁和焦虑，但睡眠更好，情绪更积极，快乐和希望。疗程有助于提高氧饱和度和消除呼吸困难。脱发停止并开始恢复。临床血液分析、血沉试验、CRP、铁蛋白、降钙素、凝血参数、血糖等参数迅速稳定下来。总的来说，冷冻疗法可以作为治疗COVID-19后综合症患者的有效标准程序，也可以与其他治疗和康复程序相结合。也就是说，冷冻疗法总是具有增效作用。