Prof. Israel Barken, who has conducted in-depth research on cryoablation-induced tumor immunity, suggests that maximizing the "distal effect" caused by local ablation is one of the directions for future research. In addition, he gave an in-depth lecture on the mechanisms related to necrosis and apoptosis induced by cryoablation, and the changes of local and distant tumor microenvironment by cryoablation.

Israel Barken教授丨第二十一届世界冷冻大会发言：题目《局部肿瘤消融时利用增强的远隔效应来控制全身转移性疾病》

Israel Barken教授在冷冻消融引起的肿瘤免疫方面有深入的研究，他提出如何最大化局部消融引起的“远隔效应”是未来研究的方向之一。另外他对冷冻消融引起坏死、凋亡的相关机制，冷冻局部和远隔肿瘤微环境改变等方面都进行深入的讲解。