For the “International Lung Cancer Day”

Cryoablations of Lung Nodules - Eradicating Lung Cancer in the Bud
November 7,2022


On the occasion of the coming International Lung Cancer Day, we ISC Secretariat visited Professor Xiao Yueyong, former president of the International Society of Cryosurgery, on the eradication of lung cancer in the early stages.

Every November is Lung Cancer Awareness Month, and November 17 is International Lung Cancer Day. Lung cancer is globally recognized as the " leading cancer ", especially in China, where the incidence and mortality rate of lung cancer is the first in the world, bringing pain and trauma to countless patients and families. The International Society of Cryosurgery (ISC) has been focusing on the treatment of lung cancer, and has made great efforts to promote cryoablation of lung cancer in recent years, and has made remarkable achievements.

Lung cancer is a malignant tumor that originated in the lung and usually has a growth cycle of months, years, or even longer before growing into an incurable larger tumor. With the update in imaging equipment and the popularization of health checkups, especially the inclusion of chest CT into routine medical checkups, more and more lung cancers are being screened out at their early stages of development. Early-stage lung cancer usually appears as small nodules or ground glass density nodules, for example, many ground glass density nodules will develop slowly and eventually develop into lung adenocarcinoma. The treatment of early-stage lung cancer is still mainly based on surgical resection, but minimally invasive percutaneous imaging-guided treatment techniques bring better solutions for patients who are unable or unwilling to undergo surgery. Through rational preoperative planning and precise probe placement, cryoablation of lung nodules can completely inactivate the tumor in situ and achieve treatment results comparable to surgical procedures with less trauma and complications. With imaging-guided cryoablation, lung cancer can be completely eradicated in the bud, completely relieving patients of their worries.

Cryoablation of lung nodules mostly adopts the treatment plan of two or more probes according to the size of the lesion. Unlike other parts of the body, the first freezing does not enable to observe the changes of the ice ball, while the coverage of the ice ball can be observed through one rewarming, and the location of the tumor and the degree of inactivation can be monitored in real-time to ensure the complete elimination of the tumor. For larger tumors, cryoablation can also achieve the effect of conformal ablation through rational probes placement. For advanced giant tumors, reasonable cryoablation can also achieve the effect of tumor reduction. In addition, the tumor in situ antigens produced after cryoablation can stimulate the body's anti-tumor immune response, which is a significant advantage and focus of cryoablation.ISC members have carried out a large number of cryoablation procedures for lung cancer every year, relieving the pain of numerous patients.

Prof. Xiao mentioned so far, the incidence and fatality of lung cancer are still ranked first, imaging-guided cryoablation for early-stage lung cancer will eventually lead to a fundamental reduction in the incidence and cure rate of lung cancer.

ISC Secretariat

November 7, 2022