On the occasion of the coming International Lung Cancer Day, we ISC Secretariat visited Professor Xiao Yueyong, former president of the International Society of Cryosurgery, on the eradication of lung cancer in the early stages.
Every November is Lung Cancer Awareness Month, and November 17 is International Lung Cancer Day. Lung cancer is globally recognized as the " leading cancer ", especially in China, where the incidence and mortality rate of lung cancer is the first in the world, bringing pain and trauma to countless patients and families. The International Society of Cryosurgery (ISC) has been focusing on the treatment of lung cancer, and has made great efforts to promote cryoablation of lung cancer in recent years, and has made remarkable achievements.
Lung cancer is a malignant tumor that originated in the lung and usually has a growth cycle of months, years, or even longer before growing into an incurable larger tumor. With the update in imaging equipment and the popularization of health checkups, especially the inclusion of chest CT into routine medical checkups, more and more lung cancers are being screened out at their early stages of development. Early-stage lung cancer usually appears as small nodules or ground glass density nodules, for example, many ground glass density nodules will develop slowly and eventually develop into lung adenocarcinoma. The treatment of early-stage lung cancer is still mainly based on surgical resection, but minimally invasive percutaneous imaging-guided treatment techniques bring better solutions for patients who are unable or unwilling to undergo surgery. Through rational preoperative planning and precise probe placement, cryoablation of lung nodules can completely inactivate the tumor in situ and achieve treatment results comparable to surgical procedures with less trauma and complications. With imaging-guided cryoablation, lung cancer can be completely eradicated in the bud, completely relieving patients of their worries.
Cryoablation of lung nodules mostly adopts the treatment plan of two or more probes according to the size of the lesion. Unlike other parts of the body, the first freezing does not enable to observe the changes of the ice ball, while the coverage of the ice ball can be observed through one rewarming, and the location of the tumor and the degree of inactivation can be monitored in real-time to ensure the complete elimination of the tumor. For larger tumors, cryoablation can also achieve the effect of conformal ablation through rational probes placement. For advanced giant tumors, reasonable cryoablation can also achieve the effect of tumor reduction. In addition, the tumor in situ antigens produced after cryoablation can stimulate the body's anti-tumor immune response, which is a significant advantage and focus of cryoablation.ISC members have carried out a large number of cryoablation procedures for lung cancer every year, relieving the pain of numerous patients.
Prof. Xiao mentioned so far, the incidence and fatality of lung cancer are still ranked first, imaging-guided cryoablation for early-stage lung cancer will eventually lead to a fundamental reduction in the incidence and cure rate of lung cancer.
ISC Secretariat
November 7, 2022
“国际肺癌日”来临之际
肺结节冷冻消融治疗-将肺癌根除在萌芽里
在“国际肺癌日”即将到来之际，ISC秘书处就早期肺癌的根除问题拜访了国际冷冻外科学会前任主席肖越勇教授。
每年11月是全球肺癌关注月，11月17日是国际肺癌日。肺癌是全球公认的“头号癌症”，特别在中国肺癌的发病率和死亡率均位于世界第一位，为无数患者和家庭带来疼痛和创伤。国际冷冻协会(ISC)一直聚焦肺癌的治疗，近年来大力推广肺癌的冷冻消融，并取得了显著的成绩。
肺癌是指原发于肺部的肿瘤，在增长成较大的肿块之前，通常都有着数月、数年甚至更长的生长周期。随着影像检查设备的更新和健康体检的普及，特别是胸部CT被纳入常规体检项目，越来越多的肺癌在发病的早期阶段就会被筛出。早期肺癌通常表现为小结节或者磨玻璃密度结节，例如很多磨玻璃密度结节会缓慢发展，并最终发展为肺腺癌。针对早期肺癌的治疗临床上目前仍以手术切除为主，而经皮影像学引导的微创诊疗技术为无法或不愿手术的患者带来了更佳的解决方案。通过合理的术前规划和精准的布针，肺部结节的冷冻消融能彻底灭活肿瘤，在更小创伤和更少并发症的前提下，达到媲美外科手术的治疗效果。通过影像学引导下的冷冻消融术完全可以将肺癌根除在萌芽里，彻底为患者解除后顾之忧。
肺结节的冷冻消融术根据病变的大小多采用两针或多针夹击的治疗方案。与其他部位不同的是，首次冷冻并不能观察到冰球的变化，而通过一次复温就能观察到冰球的覆盖范围，实时监控肿瘤的位置和灭活的程度，保证肿瘤的彻底灭活。而对于较大的肿瘤，通过合理布针，冷冻消融也能达到适形消融的效果。针对晚期的巨大肿瘤，合理的冷冻消融术也能起到减瘤的效果。另外，冷冻后产生的肿瘤原位抗原能刺激机体的抗肿瘤免疫反应，这是冷冻的一个显著优势和关注焦点。
我们的会员每年开展了大量肺癌的冷冻消融手术，为无数患者解除了病痛。肖教授提到，到目前为止，肺癌的发病率和死亡率仍然排在第一位，影像学引导下的早期肺癌冷冻消融术最终将使肺癌的发病率和治愈率得到根本的降低。
ISC秘书处
2022年11月7日